Integrating scientific knowledge with today’s most effective treatment options, Addiction Medicine: Science and Practice, 2nd Edition, provides a wealth of information on addictions to substances and behavioral addictions. It discusses the concrete research on how the brain and body are affected by addictions, improving your understanding of how patients develop addictions and how best to personalize treatment and improve outcomes. This essential text is ideal for anyone who deals with patients with addictions in clinical practice, including psychiatrists, health psychologists, pharmacologists, social workers, drug counselors, trainees, and general physicians/family practitioners.

• • Clearly explains the role of brain function in drug taking and other habit-forming behaviors, and shows how to apply this biobehavioral framework to the delivery of evidence-based treatment.

• • Provides clinically relevant details on not only traditional sources of addiction such as cocaine, opiates, and alcohol, but also more recently recognized substances of abuse (e.g., steroids, inhalants) as well as behavioral addictions (e.g., binge eating, compulsive gambling, hoarding).

• • Discusses current behavioral and medical therapies in depth, while also addressing social contexts that may affect personalized treatment.

• • Contains new information on compliance-enhancing interventions, cognitive behavioral treatments, behavioral management, and other psychosocial interventions.

• • Includes neurobiological, molecular, and behavioral theories of addiction, and includes a section on epigenetics.

• • Contains up-to-date information throughout, including a new definition of status epilepticus, a current overview of Lennox Gastaut syndrome, and updates on new FDA-approved drugs for pediatric neurological disorders.

• • Features expanded sections on evidence-based treatment options including pharmacotherapy, pharmacogenetics, and potential vaccines.

• • Addresses addiction in regards to specific populations, including adolescents, geriatric, pregnant women, and health care professionals.

• Includes contributions from expert international authors, making this a truly global reference to addiction medicine.

Contents

۱. Emerging Health Perspectives
۲. The Epidemiology of Alcohol and Drug Disorders
۳. United States Federal Drug Policy
۴. Historical Perspectives of Addiction
۵. Diagnosis and Classification of Substance Use Disorders
۶. Drug Reinforcement in Animals
۷. Role of Human Laboratory Studies in the Development of Medications for Alcohol and Substance Use Disorders
۸. Conditioning of Addiction
۹. Overlapping Striatal Circuits and Molecular Mechanisms in Rodent Models of Addiction and Depression
۱۰. The Role of Endocannabinoids in Amphetamine-Driven Actions in Dopamine Neurons : Implications for Understanding and Treating Dysfunction in the Mesolimbic Circuit
۱۱. Pain and Negative Affect
۱۲. Genetic Vulnerability to Substance Use Disorders
۱۳. The Assessment and Treatment of Addiction : Best Practices in a Direct-to-Consumer Age
۱۴. Metabolomics in Drug Response and Addiction
۱۵. Neuroimaging Findings in Substance Use Disorders
۱۶. Neurobiological Basis of Drug Reward and Reinforcement
۱۷. Neurobehavioral Toxicology of Substances of Abuse
۱۸. Animal Models of Substance Use Disorders : Motivational Perspective
۱۹. Novel Methodologies : Proteomic Approaches in Substance Abuse Research
۲۰. Neuroinflammatory Processes in Drug Addiction
۲۱. Alcohol : Clinical Aspects
۲۲. Cocaine
۲۳. Nicotine
۲۴. Cannabis : An Overview of the Empirical Literature
۲۵. Opiates and Prescription Drugs
۲۶. Clinical Aspects of Methamphetamine
۲۷. Sedative-Hypnotics and Anxiolytics
۲۸. Clinical Aspects of Inhalant Addiction
۲۹. Anabolic-Androgenic Steroids
۳۰. Caffeine
۳۱. Serotonergic Hallucinogens
۳۲. Ketamine and Phencyclidine
۳۳. The Biology and Treatment of Gambling Disorder
۳۴. Implications of Food Addiction for Understanding and Treating Binge Eating Disorder
۳۵. Compulsive Buying
۳۶. Sexual Behavior as an Addictive or Compulsive Phenomenon
۳۷. New Era of Internet Addiction Research in China
۳۸. Hoarding as a Behavioral Addiction
۳۹. Motivational Interviewing : Emerging Theory, Research, and Practice
۴۰. Cognitive Behavioral Therapy for Addiction
۴۱. Community Reinforcement Approach and Contingency Management Therapies
۴۲. Relapse Prevention and Recycling in Addiction
۴۳. Brief and e-Health Interventions for the Treatment of Alcohol or Other Drug Addiction
۴۴. Self-Help Approaches for Addictions
۴۵. Community Clinics
۴۶. Unhealthy Alcohol and Other Drug Use in Primary Care
۴۷. Criminal Justice System and Addiction Treatment
۴۸. Adolescent Neurocognitive Development and School-Based Drug Abuse Prevention and Treatment
۴۹. The Therapeutic Community for Drug Abuse Treatment : A Journey Yet Unfolding in the Recovery Movement
۵۰. Substance Use–Focused Mutual-Help Groups : Processes and Outcomes
۵۱. Pharmacotherapy for Alcoholism and Some Related Psychiatric and Addictive Disorders : Scientific Basis and Clinical Findings
۵۲. Alcohol Withdrawal : Treatment and Application
۵۳. Pharmacotherapy of Cocaine Addiction
۵۴. Opioid Overdose
۵۵. Methamphetamine
۵۶. Potential Pharmacotherapies for Cannabis Dependence
۵۷. Hallucinogens
۵۸. Molecular Genetics and the Treatment of Addiction
۵۹. Physical Considerations for Treatment Complications of Alcohol and Drug Use and Misuse
۶۰. Quadruple Diagnosis : Substance Use Disorder, Comorbid Psychopathology, Human Immunodeficiency Virus Infection, and Hepatitis C Virus Infection
۶۱. Substance Use Stigma As a Barrier to Treatment and Recovery
۶۲. Religiousness, Spirituality, and Addiction : An Evidence-Based Review
۶۳. In Silico Models of Alcohol Kinetics : A Deterministic Approach
۶۴. In Silico Models of Alcohol Dependence Treatment : A Stochastic Approach
۶۵. Dynamic and Systems-Based Models for Evaluating Hypotheses Related to Predicting Treatment Response
۶۶. Enhancing Positive Outcomes for Children of Substance-Abusing Parents
۶۷. Alcohol and Substance Abuse in African Americans
۶۸. Substance Use Disorders in Health Care Professionals
۶۹. Identification and Treatment of Alcohol or Drug Dependence in the Elderly
۷۰. Alcohol and Drugs of Abuse in Pregnant Women : Effects on the Fetus and Newborn, Mode of Action, and Maternal Treatment
۷۱. Forensic Issues
۷۲. Disability and Addiction
۷۳. The Homeless
۷۴. Opening New Vistas in Basic and Preclinical Addiction Research
۷۵. Therapeutic Use of Noninvasive Neuromodulation for Addictions
۱. National Institute on Drug Abuse (NIDA): Medications to Treat Opioid Use Disorder ∗
۲. TIP 63: Medications for Opioid Use Disorder
۳. The ASAM National Practice Guideline for the Use of Medications in the Treatment of Addiction Involving Opioid Use