In a world where kidney injury poses an ever-growing threat to human health due to aging populations and changing lifestyles, understanding and combating renal diseases have never been more critical.This book delves into cutting-edge renal disease research, where rapid developments have illuminated new technologies for diagnosis and treatment of the disease. The book systematically and comprehensively addresses clinical issues related to kidney diseases, where readers can explore topics such as hypoxia-inducible factors and renal anemia, pathogenesis of IgA nephropathy, hypertension, diabetic nephropathy, PLA2R antibodies and membranous nephropathy, immune nephropathy treatments using biological agents, renal glucose and energy metabolism, the application of SGLT2 inhibitors, and mechanisms of renal fibrosis.Written by over thirty experts who are actively shaping the field of nephrology in China and the USA, this book offers profound insights to understanding renal diseases, making it an indispensable resource for researchers, clinicians, and readers seeking to grow their knowledge on the scientific issues of kidney disease.

Contents

۱. Epidemiology and Economic Burden of CKD in China
۲. Comprehensive Understanding of Kidney Disease and Hypertension
۳. Renal Anemia. The Role of Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor
۴. Klotho and Chronic Kidney Disease
۵. Role of SGLT2 Inhibitor in Cardiorenal Protection with DKD. New Perspectives
۶. Mineralocorticoid Receptor. An Old Target But New Evidence
۷. The Immunological Mechanism Involved in Primary Glomerular Diseases
۸. Membranous Nephropathy. New Mechanisms and Therapies
۹. New Insights Into the Mechanism of Edema Formation in Nephrotic Syndrome
۱۰. What’s New on IgA Nephropathy. Pathogenesis and Therapies
۱۱. Lupus Nephritis. Research Highlights and Progress of Treatment
۱۲. Diabetic Kidney Disease. A New Horizon
۱۳. Applications of Recent Innovations in Renal Pathology
۱۴. Biologic Agents in the Treatment of Glomerular Diseases. Current Status and Future
۱۵. Acute Kidney Injury. From Bench to Bedside
۱۶. Sepsis and AKI. Pathogenesis and Therapies
۱۷. Autophagy and Acute Kidney Disease
۱۸. Current Understanding of the Transition of AKI to CKD
۱۹. Physiology of Renal Distal Nephron and its Clinical Relevance
۲۰. Renal Handling of Potassium and Potassium Disturbances
۲۱. Clinical Practice and Evaluation of the Treatment of Abnormal Phosphorus Homeostasis
۲۲. The Story Behind the Systemic Effects of CKD Acidosis
۲۳. Nuclear Receptors in Health and Kidney Disorders. New Perspectives
۲۴. Renal Fibrosis. Molecular Mechanism and Signal Pathways
۲۵. How Tubule Injury Instigates the Tubulointerstitial Inflammation and Fibrosis
۲۶. Extracellular Vesicles. The New Player in Renal Fibrosis
۲۷. Role of Renin Angiotensin System in Renal Fibrosis. New Perspectives
۲۸. Endothelin and Renal Disease
۲۹. How Mitochondria Dysfunction Affects Kidney Disease
۳۰. Strategy for Molecular Diagnosis of Kidney Disease
۳۱. Advances in the Treatment of Nephrotic Syndrome in Children
۳۲. Progress of Genetic Renal Diseases in Children
۳۳. Uromodulin Associated Kidney Disease. An Update
۳۴. Copper Homeostasis and Renal Fibrosis
۳۵. Histone Acetylation and its Clinical Implications in Chronic Kidney Disease
۳۶. New Progress in the Clinical Application of Natriuretic Peptide (Hormone)