Biochemistry, Cell and Molecular Biology, and Genetics: An Integrated Textbook by Zeynep Gromley and Adam Gromley is the first to cover molecular biology, cell biology, biochemistry (metabolism), and genetics in one comprehensive yet concise resource. Throughout the book, these topics are linked to other basic medical sciences, such as pharmacology, physiology, pathology, immunology, microbiology, and histology, for a truly integrated approach.

Key Highlights

• Easy-to-read text enhances understanding of underlying molecular mechanisms of disease
• Nearly 500 illustrations and tables help reinforce chapter learning objectives
• Textboxes throughout make connections with other preclinical disciplines
• End of unit high-order clinical vignette questions with succinct explanations help integrate basic science topics with clinical medicine

This textbook provides a robust review for medical students preparing for courses as well as exams. Dental, pharmacy, physician’s assistant, nursing, and graduate students in pre-professional/bridge programs will also find this a beneficial learning tool.

Contents

۱ Anatomy of the Cell and Organelles
۲ DNA Replication, Gene Mutations, and Repair
۳ Transcription and Regulation of Transcription
۴ Translation and Regulation of Translation
۵ Cytoskeleton
۶ Protein Sorting, Modifications, and Intracellular Traffic
۷ Membrane Transport
۸ Extracellular Matrix
۹ Cell Adhesion and Membrane Junctions
۱۰ Signal Transduction
۱۱ Cell Cycle and Control of the Cell Cycle
۱۲ Stem Cells and Hematopoiesis
۱۳ Cell Injury, Apoptosis, and Necrosis
۱۴ Hallmarks of Cancer and Cancer Biology
۱۵ Molecular Principles of Cancer Treatments and Therapies
۱۶ Enzymes and Enzyme Kinetics
۱۷ Regulation of Enzyme Activity
۱۸ Structure and Function of Proteins
۱۹ Molecular and Biological Techniques
۲۰ Plasma Proteins and the Diagnostic Use of Enzymes
۲۱ Digestion and Absorption of Carbohydrates
۲۲ Glycolysis
۲۳ Metabolism of Fructose, Galactose and the Pentose Phosphate Pathway (HMP Shunt)
۲۴ Glycogen Metabolism and Regulation
۲۵ Gluconeogenesis
۲۶ Pyruvate Dehydrogenase and Tricarboxylic Acid (TCA) Cycle
۲۷ Electron Transport Chain (ETC) and Oxidative Phosphorylation
۲۸ Oxygen Toxicity and Antioxidants
۲۹ Oxidation of Fatty Acids and Ketogenesis
۳۰ Acid Base Chemistry and Acid Base Disorders
۳۱ Glucose Homeostasis and Maintenance of Blood Glucose Concentrations
۳۲ Digestion and Absorption of Proteins
۳۳ Nitrogen Metabolism
۳۴ Amino Acid Metabolism
۳۵ Amino Acid Derivatives
۳۶ Porphyrin Heme Metabolism and Iron Homeostasis
۳۷ Nucleotide Metabolism
۳۸ Vitamins in One-Carbon Metabolism
۳۹ Digestion and Absorption of Lipids
۴۰ Synthesis of Fatty Acids and Triacylglycerols
۴۱ Metabolism of Membrane Lipids and Lipid Derivatives
۴۲ Cholesterol Metabolism
۴۳ Blood Lipoproteins
۴۴ Steroid Hormones and Vitamin D
۴۵ Nutrition and Metabolism
۴۶ Vitamins and Minerals
۴۷ DNA Packaging and Meiosis
۴۸ Cytogenetics: Chromosomal Basis of Human Diseases
۴۹ Single Gene Disorders: Autosomal Dominant and Recessive Inheritance
۵۰ Sex-linked and Non-traditional Modes of Inheritance
۵۱ Population Genetics
۵۲ Genomic Imprinting and Epigenetics
۵۳ Gene Interactions and Multifactorial Inheritance
۵۴ Personalized Medicine
۵۵ Developmental Genetics
۵۶ Cancer Genetics