The human urinary bladder is subject to a unique and extraordinarily diverse array of congenital, inflammatory, metaplastic, and neoplastic abnormalities. This book provides contemporary, comprehensive, and evidence-based practice information for pathologists, urologists, oncologists, and other medical professionals.

In Bladder Pathology, a full spectrum of pathologic conditions that afflict the bladder and urothelium are described and lavishly illustrated. With its emphasis on diagnostic criteria and differential diagnoses, this book is of particular value to practicing pathologists—assisting in the pathologist’s recognition, understanding, and accurate interpretation of the light microscopic findings in bladder specimens.

Features and benefits of this new volume include:

• ۱,۷۴۱ high-quality color illustrations and 112 tables to illustrate the wide range of pathologic and clinical features of the urinary tract
• An evidence-based approach to diagnosis and patient management for infectious, nonneoplastic, and neoplastic conditions
• Recent advances in the molecular genetics of the urinary bladder with discussion of its current or potential impact on diagnosis and personalized patient care
• Emphasis on the scientific validation of current diagnostic methods and their direct application in clinical practice

Bladder Pathology is a cutting-edge resource that not only offers comprehensive research and clinical information for practicing surgical pathologists, urologists, oncologists, and their clinical colleagues, but also captures a genuine sense of excitement about recent advances in this vital, ever-evolving field.

Contents

1. Normal Anatomy and Histology
2. Inflammatory and Infectious Conditions
3. Urothelial Metaplasia and Hyperplasia
4. Polyps and Other Nonneoplastic Benign Conditions
5. Benign Epithelial Tumors
6. Flat Urothelial Lesions with Atypia and Urothelial Dysplasia
7. Urothelial Carcinoma in Situ
8. Bladder Cancer: General Features
9. Grading of Bladder Cancer
10. Stage pT1 Urothelial Carcinoma
11. Staging of Bladder Cancer
12. Histologic Variants of Urothelial Carcinoma
13. Adenocarcinoma and Its Putative Precursors and Variants
14. Squamous Cell Carcinoma and Other Squamous Lesions
15. Neuroendocrine Tumors
16. Sarcomatoid Carcinoma (Carcinosarcoma)
17. Bladder Tumors with Inverted Growth
18. Congenital Disorders and Pediatric Neoplasms
19. Soft Tissue Tumors
20. Lymphoid and Hematopoietic Tumors
21. Urothelial Carcinoma Following Augmentation Cystoplasty
22. Other Rare Tumors
23. Secondary Tumors
24. Treatment Effects
25. Handling and Reporting of Bladder Specimens
26. Diagnostic Immunohistochemistry
27. Pathology of the Urachus
28. Pathology of Renal Pelvis, Ureter, and Urethra
29. Molecular Determinants of Tumor Recurrence
30. Urinary Cytology
31. Evaluation of Hematuria and Urinalysis
32. Urine-based Biomarkers
33. Tissue-based Biomarkers
34. Molecular Pathology of Bladder Cancer