Cognitive Plasticity in Neurologic Disorders describes and specifies the cognitive impact of neuroplastic processes in key neurologic disorders and syndromes. It is set apart from previous works in this area by its emphasis on the changing quality of neurocognition, demonstrating that this dynamic nature emerges from the neuroplastic processes at work in both mild and severe states of brain disease or injury. This resource describes the ways neurological illness or trauma (or attempts to treat patients with such conditions) can trigger neuroplastic mechanisms in the brain, inducing cognitive reorganization and remapping of brain networks.

Each chapter shows how the cognitive and behavioral presentation of the disorder mirrors the changing neurobiologic context, and displays the numerous techniques being employed (e.g. behavior and rehabilitation therapies, electrical stimulation, and computer/machine neuromodulation of brain signals) underlying the neurobiology in ways that facilitate adaptive plasticity and cognitive recovery. An important feature of the book involves characterizing the degree to which the mechanistic principles governing neuroplastic responses and cognitive reorganization in the brain have been elucidated, making clear that it is these principles which will allow us to further develop rational rehabilitative therapies, match patients to appropriate treatments, and even begin to predict clinical treatment outcomes.

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Contents

۱ Recovery, Compensation, and Reorganization in Neuropathology: Levels of Conceptual and Methodological Challenges
۲ Seizure-Induced Neuroplasticity and Cognitive Network Reorganization in Epilepsy
۳ Neuroplastic Mechanisms of Language Recovery After Stroke
۴ Cognitive Plasticity in Parkinson’s Disease
۵ Neuroplasticity in Multiple Sclerosis
۶ Plasticity of Cognition in Brain Gliomas
۷ Connectivity Modeling and Neuroplasticity After Traumatic Brain Injury
۸ Aberrant Brain Plasticity in Autism Spectrum Disorders
۹ Cognitive Plasticity in Healthy Older Adults, Mild Cognitive Impairment, and Alzheimer’s Disease: Contributory Factors and Treatment Responses
۱۰ Plasticity in Prefrontal Cortical Networks After Brain Injury: Finding the Optimal Paths
۱۱ Organic Amnesia: What Factors Determine How Much It Recovers Over Time?
۱۲ Aging-Related Changes in Neural Substrates of Motor and Cognitive Systems
۱۳ Spatially Biased Decisions: Toward a Dynamic Interactive Model of Visual Neglect
۱۴ Neuroplasticity in Apraxia Recovery
۱۵ Clinical Brain-Machine Interfaces
۱۶ Assessment and Enhancement of Human Brain Plasticity Using Electromagnetic Stimulation