An increased understanding of the biology and molecular characterization of skull base tumors has led to innovative new approaches. Endoscopic tumor resection, surgical reconstruction, and advances in radiation delivery, chemotherapy, and targeted biologic therapy, have greatly expanded treatment options for patients with these challenging tumors. The updated second edition of Comprehensive Management of Skull Base Tumors by master surgeons Ehab Hanna, Franco DeMonte, and an impressive group of global experts reflects expanded knowledge of skull base tumors and evidence-based advances.

This generously illustrated second edition is organized into three sections with 42 chapters. Section I features expanded coverage of endonasal skull base anatomy and surgical principles, as well as radiotherapeutic advances such as proton therapy and stereotactic radiation. Section II is focused on site-specific procedures with emphasis on surgical approaches, and Section III focuses on tumor-specific considerations with emphasis on multidisciplinary treatment approaches. Core topics of this thorough book include pathology, genetics, diagnostic considerations, surgical reconstruction, rehabilitation, chemotherapy, functional outcomes, quality of life issues, neurocognitive assessment, and cerebrovascular management.

Key Features

• In-depth discussion of anatomic regions of the cranial base, including surgical anatomy, regional pathology, differential diagnosis, clinical assessment, diagnostic imaging, and surgical approaches
• Incidence, epidemiology, pathology, staging, multidisciplinary treatment, outcome, and prognosis for a wide range of neoplasms including squamous cell carcinoma, chondrosarcomas, chordomas, meningiomas, schwannomas, paragangliomas, pituitary adenomas, craniopharyngiomas, epidermoids, and fibro-osseous lesions
• Outstanding illustrations, surgical and clinical photos, imaging, tables, and videos new to this edition, enhance understanding of complex skull base tumors

The most comprehensive resource available today on the management and treatment of skull base tumors, this book is essential reading for neurosurgical and otolaryngology residents. It will also benefit surgeons who specialize in oromaxillofacial, craniofacial, and plastic and reconstructive surgery.

Contents

۱ Surgical Anatomy of the Cranial Base: Transcranial and Endonasal Approaches
۲ The Pathology of Tumors and Tumorlike Lesions of the Skull Base
۳ Imaging of Skull Base Neoplasms
۴ Head, Neck, and Neuro-otologic Assessment of Patients with Skull Base Tumors
۵ Anesthesia and Intraoperative Monitoring of Patients with Skull Base Tumors
۶ Endoscopic Endonasal Skull Base Surgery
۷ Reconstruction of Skull Base Defects
۸ Radiotherapy for Skull Base Tumors: Principles and Techniques
۹ Clinical Applications of Radiotherapy for Skull Base Tumors
۱۰ Management of Benign Skull Base Tumors in Neuro-oncology: Systemic Cytotoxic and Targeted Therapies
۱۱ Rehabilitation of Speech and Swallowing of Patients with Tumors of the Skull Base
۱۲ Neuropsychological Assessment of Patients with Skull Base Tumors
۱۳ Cerebrovascular Management in Skull Base Tumors
۱۴ Quality of Life and Measures of Outcome for Patients with Skull Base Tumors
۱۵ Pediatric Skull Base Surgery
۱۶ Surgical Management of Tumors of the Nasal Cavity, Paranasal Sinuses, Orbit, and Anterior Skull Base
۱۷ Nasopharyngeal Carcinoma
۱۸ Clival Tumors
۱۹ Tumors of the Infratemporal Fossa
۲۰ Tumors of the Parapharyngeal Space
۲۱ Tumors of the Temporal Bone
۲۲ The Evaluation and Management of Sellar Tumors
۲۳ Tumors of the Cavernous Sinus and Parasellar Space
۲۴ Tumors of the Petrous Apex
۲۵ Tumors of the Cerebellopontine Angle
۲۶ Tumors of the Jugular Foramen
۲۷ Tumors of the Craniovertebral Junction
۲۸ Tumors of the Orbit
۲۹ Squamous Cell Carcinoma of the Nasal Cavity and Paranasal Sinuses
۳۰ Nonsquamous Cell Carcinoma of the Nasal Cavity and Paranasal Sinuses
۳۱ Esthesioneuroblastoma
۳۲ Melanoma of the Nasal Cavity and Paranasal Sinuses
۳۳ Sarcomas of the Skull Base
۳۴ Angiofibromas and Other Vascular Tumors of the Skull Base
۳۵ Chordomas and Chondrosarcomas of the Skull Base
۳۶ Meningiomas
۳۷ Schwannomas of the Skull Base
۳۸ Paragangliomas of the Head and Neck
۳۹ Pituitary Adenomas
۴۰ Craniopharyngiomas
۴۱ Epidermoids, Dermoids, and Other Cysts of the Skull Base
۴۲ Fibro-Osseous Lesions of the Skull Base