Offering up-to-date, comprehensive coverage of disease progression, diagnosis, management, and prognosis, Textbook of Pediatric Rheumatology is the definitive reference in the field. For physicians caring for children with rheumatic diseases, this revised 8th Edition is an unparalleled resource for the full spectrum of rheumatologic diseases and non-rheumatologic musculoskeletal disorders in children and adolescents. Global leaders in the field provide reliable, evidence-based guidance, highlighted by superb full-color illustrations that facilitate a thorough understanding of the science that underlies rheumatic disease.

• Offers expanded coverage of autoinflammatory diseases, plus new chapters on Takayasu Arteritis and Other Vasculitides, Mechanistic Investigation of Pediatric Rheumatic Diseases, Genetics and Pediatric Rheumatic Diseases, and Global Issues in Pediatric Rheumatology.
• Reflects the changes in diagnosis, monitoring, and management that recent advances have made possible.
• Covers the latest information on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies, helping you choose treatment protocols based on the best scientific evidence available today.
• Features exhaustive reviews of the complex symptoms, signs, and lab abnormalities that characterize these clinical disorders.

Review

The authoritative resource you need for complete coverage of this complex specialty

Contents

۱. Structure and Function
۲. Genetics and Pediatric Rheumatic Diseases
۳. Mechanistic Investigation of Pediatric Rheumatic Diseases
۴. Inflammation and Its Mediators
۵. Adaptive Immunity and Autoimmunity
۶. Understanding Clinical Investigations
۷. Clinical Outcome Measures in Pediatric Rheumatic Diseases
۸. Pain and Its Assessment
۹. Imaging in Pediatric Rheumatic Diseases
۱۰. Laboratory Investigations
۱۱. Principles in the Management of Patients with Rheumatic Disease
۱۲. Global Issues in Pediatric Rheumatology
۱۳. Therapeutics : Nonbiologics
۱۴. Therapeutics : Biologics and Small Molecules
۱۵. Nonmedical Therapies in Pediatric Rheumatic Diseases
۱۶. Juvenile Idiopathic Arthritis : Classification and Basic Concepts
۱۷. Systemic Juvenile Idiopathic Arthritis
۱۸. Polyarticular Juvenile Idiopathic Arthritis
۱۹. Oligoarticular Juvenile Idiopathic Arthritis
۲۰. Enthesitis-Related Arthritis
۲۱. Psoriatic Juvenile Idiopathic Arthritis
۲۲. Uveitis in Juvenile Idiopathic Arthritis
۲۳. Systemic Lupus Erythematosus, Mixed Connective Tissue Disease, and Undifferentiated Connective Tissue Disease
۲۴. Antiphospholipid Syndrome
۲۵. Neonatal Lupus Erythematosus
۲۶. Juvenile Dermatomyositis and Other Inflammatory Muscle Diseases
۲۷. Juvenile Systemic Sclerosis
۲۸. Localized Scleroderma and Eosinophilic Fasciitis
۲۹. Sjögren Syndrome and Immunoglobulin-G4 Disease
۳۰. Raynaud Phenomenon and Vasomotor Syndromes
۳۱. Inflammatory Central Nervous System Disorders
۳۲. Vasculitis and Its Classification
۳۳. Immune Complex Small-Vessel Vasculitis : IgA Vasculitis (Henoch–Schönlein) and Hypersensitivity Vasculitis
۳۴. Polyarteritis Nodosa
۳۵. Kawasaki Disease
۳۶. Antineutrophil Cytoplasmic Antibody Associated Vasculitis
۳۷. Takayasu Arteritis and Other Vasculitides
۳۸. Behçet Disease
۳۹. Periodic Fever Syndromes and Other Inherited Autoinflammatory Diseases
۴۰. Autoinflammatory Bone Diseases
۴۱. Pediatric Sarcoidosis
۴۲. Macrophage Activation Syndrome
۴۳. Primary Immunodeficiencies and Rheumatic Diseases
۴۴. Infectious Arthritis and Osteomyelitis
۴۵. Lyme Disease
۴۶. Reactive Arthritis
۴۷. Skeletal Malignancies and Related Disorders
۴۸. The Impact of Rheumatic Diseases and Their Treatment on Bone Strength Development in Childhood
۴۹. Skeletal Dysplasias
۵۰. Noninflammatory Musculoskeletal Pain
۵۱. Musculoskeletal Manifestations of Inflammatory Bowel Disease
۵۲. Musculoskeletal Manifestations of Systemic Disease
۵۳. Pain Amplification Syndromes
۵۴. Primary Disorders of Connective Tissue